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Manual material handling systems (MMHS) are probably the most common systems for handling, moving, storing, retrieving, and managing materials. ProModel easily allows you to model manual labor. With shifts, breaks, and downtimes (illness, training, etc.), model people as resources.
Whether carrying parts from one station to another or stocking shelves in a grocery store, people can be modeled as resources to do just about anything in ProModel. Such resources are dynamic and move along assigned path networks.
Since people can think, you can model them very much like automated guided vehicles with on-board vehicle sensing.